Handling linkage disequilibrium in linkage analysis using dense single-nucleotide polymorphisms
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چکیده
منابع مشابه
Handling linkage disequilibrium in linkage analysis using dense single-nucleotide polymorphisms
The presence of linkage disequilibrium violates the underlying assumption of linkage equilibrium in most traditional multipoint linkage approaches. Studies have shown that such violation leads to bias in qualitative trait linkage analysis when parental genotypes are unavailable. Appropriate handling of marker linkage disequilibrium can avoid such false positive evidence. Using the rheumatoid ar...
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ژورنال
عنوان ژورنال: BMC Proceedings
سال: 2007
ISSN: 1753-6561
DOI: 10.1186/1753-6561-1-s1-s161